MARYVILLE NURS 611 PATHO
ACTUAL EXAM QUESTIONS AND
CORRECT DETAILED ANSWERS
|ALREADY GRADED A+
Apoptosis - ✔✔✔✔-A programmed cell death that is regulated
or programmed. Cellular self-destruction for elimination or
unwanted cell populations
Necrosis - ✔✔✔✔-Rapid loss of the plasma membrane
structure, organelle swelling, mitochondria dysfunction
What is the #1 cause of cellular injury leading to necrosis
(especially the kidney and heart) - ✔✔✔✔-hypoxia
What is the #1 cause of hypoxia? - ✔✔✔✔-ischemia
Main component of a cell - ✔✔✔✔-nucleus
What does the nucleus contain? - ✔✔✔✔-nucleolus
What is the nucleolus composed of? - ✔✔✔✔-RNA, most of
cellular DNA, DNA binding proteins, and histones
Why are histone important? - ✔✔✔✔-histones bind to DNA and
fold it into chromosomes (chromatin) which is essential for cell
division
What are ribosomes? - ✔✔✔✔-RNA-protein complexes
(nucleoproteins) that are synthesized in the nucleolus and
secreted into the cytoplasm through pores in the nuclear
envelope called nuclear pore complexes (NPCs)
Where can ribosomes be found? - ✔✔✔✔-cytoplasm and rough
ER
what are ribosomes chief function? - ✔✔✔✔-provides sits for
cellular protein synthesis
What is the Golgi apparatus (complex)? - ✔✔✔✔-a network of
flatten, smooth membranes and vesicles frequently located near
the nucleus of the cell
What does the Golgi apparatus do? - ✔✔✔✔-takes proteins from
the ER and processes/packages them into small membranebound vesicles called "secretory vesicles, and refines and
directs traffic in the cell
What are lysosomes and what do they do? - ✔✔✔✔-maintain
cellular health by removal of toxic cellular components, removal
of useless organelles, termination of signal transduction, and
signals cellular adaption
How does aging affect lysosomes? - ✔✔✔✔-leads to
progressive loss of lysosomal efficiency which declines the
regenerative capacity of organs and tissue
What functions do lysosomal components integrate? - ✔✔✔✔-
nutrient abundance, energy levels, and cell stressors and will
translate them into instructions that regulate cellular
metabolism toward either proliferation or inactivity
What is mitochondria responsible for? - ✔✔✔✔-cellular
respiration, cellular metabolism , and energy production
What does the inner membrane of mitochondria contain? -
✔✔✔✔-enzymes of the respiratory chain and are essential to
the process of oxidative phosphorylation that generates most of
the cell's ATP
The mitochondrial matrix contains what kind of pathways (1),
involve what two things (2), and metabolizes what three things
(3)? - ✔✔✔✔-1- metabolic
2- urea and heme synthesis
3- carbs, proteins, and lipids
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